产品货号：
Z26920
中文名称：
SNW1抗体
英文名称：
Anti-SNW1 Antibody (C-Term)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SNW1 Antibody (C-Term) |
| 指标别名 | Bx42;NCOA 62;Nuclear protein SkiP;Prp45;PRPF45;Ski interacting protein;SKIIP;SKIP;SNW domain containing 1;SNW1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IF |
| 基因名称 | SNW1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This SNW1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 464-497 amino acids from human SNW1. |
| 计算分子量 | 61kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Involved in transcriptional regulation.Modulates TGF- beta-mediated transcription via association with SMAD proteins,MYOD1-mediated transcription via association with PABPN1,RB1- mediated transcriptional repression,and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1.Is involved in NOTCH1-mediated transcriptional activation.Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD.Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters.Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC,MEN1 and TRRAP to the HIV promoter.Functions as a splicing factor in pre-mRNA splicing.Is required in the specific splicing of CDKN1A pre-mRNA;the function probbaly involves the recruitment of U2AF2 to the mRNA.Is proposed to recruit PPIL1 to the spliceosome.May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. |
| Uniprot ID | Q13573 |
相关搜索：SNW1抗体，SNW1(C-Term)多抗，Anti-SNW1 Antibody (C-Term)